Tobacco Cessation for People Living with HIV
Research
Quit4Life+ is supported by a comprehensive program of research designed to understand not only whether the intervention works, but also how it should be designed, delivered, and implemented to have the greatest real-world impact.
The research spans the full lifecycle of the project. Formative research helped shape the intervention and ensure that it reflects the needs, experiences, and preferences of the people it is intended to serve. Stigma-focused research examines how stigma may influence smoking, quitting, engagement with cessation support, and the ways in which cessation interventions are communicated and delivered. Implementation science research explores the factors that can support or hinder adoption, delivery, reach, and sustainability in real-world settings. Finally, a randomized controlled trial evaluates the effectiveness of the Quit4Life intervention.
Together, these studies provide a more complete picture of Quit4Life+, from the evidence and perspectives that informed its development, to its effectiveness, to the conditions needed for successful implementation and scale-up.
Explore the complete study protocols, study tools and instruments, and data sharing resources for the Quit4Life research program.
Research Ethics and Regulatory Approvals
Each Quit4Life research protocol was reviewed and approved by the relevant institutional research ethics committees and national regulatory authorities in each participating country. Approval and protocol numbers are listed below:
Makerere University School of Public Health Research Ethics Committee: 2021-178
Uganda National Council for Science and Technology: HS1762ES
University of Zambia Biomedical Research Ethics Committee: 2377-2021
Zambia National Health Research Authority: 2377-2021
University of Maryland: 2349242-1
University of Southern California: HS-22-00006
Trial registration: ClinicalTrials.gov Identifier NCT05487807.
NCI project page: https://reporter.nih.gov/project-details/11418603#description
Registered August 4, 2022, https://clinicaltrials.gov/ct2/show/record/NCT05487807